CURRICULUM VITAE
David Stafford, Ph.D.
Assistant Professor of Psychology
Centenary College of Louisiana
2911 Centenary Boulevard
Shreveport, LA 71134
318-841-7269 (office)
318-869-5795 (FAX)
318-226-0004 (home)
dstaffor@centenary.edu (e-mail)
Education:
B.A. from West Virginia University, 1991, in Psychology
M.S. from the University of Florida, 1994, in Psychology
Ph.D. from the University of Florida, 1996, in Psychology
Post-Doctoral Fellow, Instructor, and Research Associate at LSUHSC, Shreveport, 1996-2001
Awards and honors:
Mary Laidley Memorial Scholarship (1988-1991)
Quin Curtis Award Winner (outstanding undergraduate in Psychology, 1991)
Graduated Summa Cum Laude, Psychology Honors Program, University Honors Program (1991)
Phi Beta Kappa (1991)
College of Liberal Arts and Sciences Fellowship (1991-1994)
National Institute on Drug Abuse Director's Travel Award (1999)
College on Problems of Drug Dependence Travel Award (1999)
Mattie Allen Broyles Inaugural-Year Eminent Scholars Chair (2001-2002)
Centenary Research Professor of Social Sciences (2001-2002)
Grant support:
NRSA Post-doctoral grant DA 05877, activated 11-2-1998, renewed 9-24-1999 and 9-14-2000
Title: Drug effects on cocaine-paired conditioned reinforcers
Teaching experience:
With undergraduates: Psychopharmacology: drugs of abuse (Lecturer, 1999-2000)
Behavioral neuroscience and applied behavior analysis (Lecturer, 1996-1998)
Introduction to learning and behavior (Course Instructor, 1993)
Laboratory in learning and behavior (Teaching Assistant, 1993-1994)
Introduction to learning and behavior (Teaching Assistant, 1991-1992)
With graduate students: Behavioral toxicology (Lecturer, 2001)
Drug addiction: neuropharmacology and behavior (Lecturer, 2000)
Computer programming for behavioral experiments (Lecturer, 2000)
Introduction to behavioral pharmacology (Lecturer, 1999)
Conditioned reinforcement and behavioral pharmacology (Lecturer, 1999)
Psychopharmacological research with humans (Lecturer, 1999)
Neuropharmacology (Lecturer, 1997)
With medical students: Patient-oriented problem solving system in pharmacology (Leader, 1998-2000)
Professional experience:
Guest reviewer for: Drug and Alcohol Dependence
Journal of the Experimental Analysis of Behavior
Pharmacology, Biochemistry, and Behavior
Psychopharmacology
Publications:
1. Stafford, D., Branch, M.N., & Hughes, C.E. (1994). Persistence of tolerance to effects of cocaine on schedule-controlled behavior in pigeons. Behavioural Pharmacology, 5, 581-590.
2. Stafford, D. & Branch, M.N. (1996). Relations between dose magnitude, subject sensitivity, and the development of tolerance to cocaine-induced behavioral disruptions in pigeons. Behavioural Pharmacology, 7, 324-333.
3. Glowa, J.R., LeSage, M.G., Stafford, D., & Vocci, F. (1997). Novel pharmacotherapies for cocaine abuse - 1995 to present. Expert Opinion on Therapeutic Patents, 7, 1459-1476.
4. Stafford, D. & Branch, M.N. (1998). Effects of step size and break-point criterion on progressive-ratio performance. Journal of the Experimental Analysis of Behavior, 70, 123-138.
5. Stafford, D., LeSage, M.G., & Glowa, J.R. (1998). Progressive-ratio schedules of drug delivery in the analysis of drug self-administration: a review. Psychopharmacology, 139, 169-184.
6. LeSage, M.G., Stafford, D., & Glowa, J.R. (1999). Preclinical research on cocaine self-administration: environmental determinants and their interactions with pharmacological treatment. Neuroscience & Biobehavioral Reviews, 23, 717-741.
7. Stafford, D., LeSage, M.G., & Glowa, J.R. (1999). Effects of phentermine on responding maintained by progressive-ratio schedules of cocaine and food delivery in rhesus monkeys. Behavioural Pharmacology, 10, 775-784.
8. Lewis, D.B., Matecka, D., Zhang, Y., Hsin, L.-W., Dersch, C.M., Stafford, D., Glowa, J.R., Rothman, R.B., & Rice, K.C. (1999). Oxygenated analogs of 1-[(2-Diphenylmethoxy)ethyl]- and 1-[2-[Bis-(4-fluorphenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909) as potential extended-action cocaine-abuse therapeutic agents. Journal of Medicinal Chemistry, 42, 5029-5042.
9. Stafford, D., Rice, K.C., Lewis, D.B., & Glowa, J.R. (2000). Response requirements and unit dose modify the effects of GBR 12909 on cocaine-maintained behavior. Experimental and Clinical Psychopharmacology, 8, 539-548.
10. LeSage, M.G., Stafford, D., & Glowa, J.R. (2000). Abuse liability of the anesthetic propofol: self-administration of propofol in rats under fixed-ratio schedules of drug delivery. Psychopharmacology, 153, 148-154.
11. Beyer, C.E., Stafford, D., LeSage, M.G, Glowa, J.R., & Steketee, J.D. (2001). Repeated exposure to inhaled toluene sensitizes neurochemical and locomotor responses to acute cocaine in rats. Psychopharmacology, 154, 198-204.
12. Stafford, D., LeSage, M.G., Rice, K.C., & Glowa, J.R. (2001). A comparison of cocaine-, phentermine-, and GBR 12909-reinforced progressive-ratio responding in rhesus monkeys. Drug and Alcohol Dependence, 62, 41-47.
13. LeSage, M.G., Stafford, D., & Glowa, J.R. (accepted with revision). Effects of dexfenfluramine and phentermine on food intake and performance under simple or multiple progressive-ratio schedules of food-delivery in rats. Journal of the Experimental Analysis of Behavior.
14. Glowa, J.R. & Stafford, D. (submitted). Abuse potential of toluene.
15. Stafford, D. & Glowa, J.R. (submitted). Effects of baclofen on cocaine- and food-maintained responding in rhesus monkeys.
16. Hsin, L.-W., Dersch, C.M., Baumann, M.H., Horel, R., Stafford, D., Glowa, J.R., Rothman, R.B., & Rice, K.C. (submitted). Synthesis and biological activities of chiral hydroxyl-containing derivatives of 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]- and 1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazines (GBR 12909 and GBR 12935). The development of long-acting dopamine transporter ligands as potential cocaine-abuse therapeutic agents.
17. Stafford, D., LeSage, M.G., & Glowa, J.R. (submitted; revision in progress). Progressive-ratio step size influences the effects of d-amphetamine.
18. Glowa, J.R. & Stafford, D. (in preparation). The effects of morphine and naloxone on multiple fixed-ratio and progressive-ratio fentanyl-maintained performance in rhesus monkeys.
19. Glowa, J.R., Stafford, D., & Barrett, J.E. (in preparation). Effects of WAY-141839-4 and chlordiazepoxide on punished and non-punished responding in rhesus monkeys.
Invited presentations:
1. The effects of step size and break-point criterion on behavior observed under progressive-ratio schedules of reinforcement. (1996). University of North Carolina at Wilmington.
2. Examining behavioral effects of stimulants and potential treatments for cocaine abuse using nonhuman subjects. (2000). Texas Christian University.
3. The pharmacology of impulsivity. (2000 and 2001). Louisiana State University Health Sciences Center, The College of Charleston, The University of South Alabama, Illinois State University, and Centenary College of Louisiana.
Conference posters and presentations (published):
1. Stafford, D. & Glowa, J.R. (1997). Gender and strain differences in food-restriction-induced hyperactivity and a possible role of corticosterone. Neuroscience Abstracts, 23, 1080.
2. Stafford, D., LeSage, M.G., & Glowa, J.R. (1997). Reinforced and extinguished behavior using two progressive-ratio schedules of cocaine delivery. NIDA Research Monograph, 178, 211.
3. LeSage, M.G., Stafford, D., & Glowa, J.R. (1997). Effects of phentermine in rhesus monkeys performing under progressive-ratio schedules of cocaine and food delivery. NIDA Research Monograph, 178, 141.
4. Stafford, D. & Glowa, J.R. (1998). Effects of cocaine and GBR 12909 on cardiac functioning in rhesus monkeys. Neuroscience Abstracts, 24, 2170.
5. Stafford, D., LeSage, M.G., & Glowa, J.R. (1999). Ratio size and unit dose modify the effects of GBR 12909 pretreatment on food- and cocaine-maintained responding. NIDA Research Monograph, 179, 115.
6. LeSage, M.G., Stafford, D., & Glowa, J.R. (1999). Comparison of the reinforcing effects of cocaine, phentermine, and GBR 12909 in rhesus monkeys. NIDA Research Monograph, 179, 154.
7. Glowa, J.R. & Stafford, D. (1999). Effects of drugs on food- and fentanyl-maintained responding in rhesus monkeys. NIDA Research Monograph, 179, 242.
8. Stafford, D., Rice, K.C., & Glowa, J.R. (2000). GBR 12909 decanoate can produce long-lasting decreases in cocaine-reinforced progressive-ratio responding. NIDA Research Monograph, 180, 257.
9. Glowa, J.R., Stafford, D., Hsin, L.W., Lewis, D., & Rice, K.C. (2000). Effects of hydroxylated analogs of GBR 12909 on responding maintained under mult chain FI FR schedules of food and cocaine presentation. NIDA Research Monograph, 180, 114.
10. LeSage, M.G., Stafford, D., Feltenstein, M., & Glowa, J.R. (2000). Examination of the reinforcing effects of intravenous delivery of propofol, halothane, and 1,1,1-trichloroethane in rats. NIDA Research Monograph, 180, 184.
11. Hsin, L., Dersch, C.M., Horel, R., Stafford, D., Glowa, J.R., Rothman, R.B., & Rice, K.C. (2000). Synthesis and structure-activity relationships of hydroxyl-containing derivatives of GBR 12909. NIDA Research Monograph, 180, 71.
12. Stafford, D., & Glowa, J.R. (in press). Effects of intravenous baclofen pretreatment on food- and cocaine-maintained responding in rhesus monkeys. College on Problems of Drug Dependence.
13. Stafford, D., Beyer, C.E., LeSage, M., Glowa, J.R., & Steketee, J.D. (in press). Repeated exposure to inhaled toluene sensitizes neurochemical and locomotor responses to acute cocaine in rats. Neuroscience Abstracts.
Conference posters and presentations (unpublished):
1. Stafford, D., Courtney, K., & Perone, M. (1991). Conditioned reinforcing functions of stimuli correlated and uncorrelated with food. Eighth Annual Meeting of the Southeastern Association for Behavior Analysis, Charleston, S.C.
2. Stafford, D. & Branch, M.N. (1993). Acute effects of cocaine on pigeons' keypecking maintained by a multiple progressive-ratio fixed-ratio schedule of reinforcement. Nineteenth Annual Convention of the Association for Behavior Analysis, Chicago, IL.
3. Stafford, D. & Branch, M.N. (1993). Observing behavior in pigeons: the effects of stimuli correlated with different reinforcer magnitudes. Tenth Annual Meeting of the Southeastern Association for Behavior Analysis, Chapel Hill, N.C.
4. Stafford, D. & Branch, M.N. (1993). Observing responding during a three-component schedule of reinforcement: a test of the delay-reduction hypothesis. Nineteenth Annual Convention of the Association for Behavior Analysis, Chicago, IL.
5. Stafford, D. & Branch. M.N. (1994). Acute and chronic effects of cocaine on fixed-ratio keypecking by pigeons: a dose-response analysis. Twentieth Annual Convention of the Association for Behavior Analysis, Atlanta, GA.
6. Stafford, D. & Branch, M.N. (1994). Effects of increment size on food-maintained progressive-ratio responding by pigeons. Eleventh Annual Meeting of the Southeastern Association for Behavior Analysis, Savannah, GA.
7. Stafford, D. & Branch, M.N. (1994). Observing responding during a three-component schedule of reinforcement II: a case of behavioral hysteresis? Twentieth Annual Convention of the Association for Behavior Analysis, Atlanta, GA.
8. Stafford, D. & Branch, M.N. (1995). Effects of increment size on food-maintained progressive-ratio responding by pigeons II. Twenty-first Annual Convention of the Association for Behavior Analysis, Washington, D.C.
9. Stafford, D. & Branch, M.N. (1996). Effects of increment size and break-point criterion on food-maintained progressive-ratio responding by pigeons III. Twenty-second Annual Convention of the Association for Behavior Analysis, San Francisco, CA.
10. Stafford, D., LeSage, M.G., & Glowa, J.R. (1996). Progressive-ratio schedules of reinforcement are valuable tools in the analysis of drug self-administration. LSU Alcohol and Drug Abuse Conference, New Orleans, LA.
11. LeSage, M.G., Stafford, D., & Glowa, J.R. (1996). A review of recent findings of laboratory studies of drug effects on cocaine self-administration. LSU Alcohol and Drug Abuse Conference, New Orleans, LA.
12. Glowa, J.R., LeSage, M.G., & Stafford, D. (1996). The development of dopamine reuptake inhibitors as potential pharmacotherapies for cocaine abuse. LSU Alcohol and Drug Abuse Conference, New Orleans, LA.
13. LeSage, M.G., Stafford, D., & Glowa, J.R. (1999). Effects of anorectic drugs on progressive-ratio performance and food intake in rats. Twenty-fifth Annual Convention of the Association for Behavior Analysis, Chicago, IL.
14. Bossart, M., Stafford, D., & Glowa, J.R. (2001). Effects of psychomotor stimulants on food-maintained progressive-ratio responding in rats. Twenty-seventh Annual Convention of the Association for Behavior Analysis, New Orleans, LA.